Biotech & Health

With $21M in funding, Code Ocean aims to help researchers replicate data-heavy science

Comment

Illustration showing scientists using the Code Ocean product as if it were a real physical thing.
Image Credits: Code Ocean

Every branch of science is increasingly reliant on big data sets and analysis, which means a growing confusion of formats and platforms — more than inconvenient, this can hinder the process of peer review and replication of research. Code Ocean hopes to make it easier for scientists to collaborate by making a flexible, shareable format and platform for any and all data sets and methods, and it has raised a total of $21 million to build it out.

Certainly there’s an air of “Too many options? Try this one!” to this (and here’s the requisite relevant XKCD). But Code Ocean isn’t creating a competitor to successful tools like Jupyter or GitLab or Docker — it’s more of a small-scale container platform that lets you wrap up all the necessary components of your data and analysis in an easily shared format, whatever platform they live on natively.

The trouble appears when you need to share what you’re doing with another researcher, whether they’re on the bench next to you or at a university across the country. It’s important for replication purposes that data analysis — just like any other scientific technique — be done exactly the same way. But there’s no guarantee that your colleague will use the same structures, formats, notation, labels and so on.

That doesn’t mean it’s impossible to share your work, but it does add a lot of extra steps as would-be replicators or iterators check and double check that all the methods are the same, that the same versions of the same tools are being used in the same order, with the same settings, and so on. A tiny inconsistency can have major repercussions down the road.

Turns out this problem is similar in a way to how many cloud services are spun up. Software deployments can be as finicky as scientific experiments, and one solution to this is containers, which like tiny virtual machines include everything needed to accomplish a computing task, in a portable format compatible with many different setups. The idea is a natural one to transfer to the research world, where you can tie up all in one tidy package the data, the software used and the specific techniques and processes used to reach a given result. That, at least, is the pitch Code Ocean offers for its platform and “Compute Capsules.”

Diagram showing how a "compute capsule" includes code, environment, and data.
Image Credits: Code Ocean

Say you’re a microbiologist looking at the effectiveness of a promising compound on certain muscle cells. You’re working in R, writing in RStudio on an Ubuntu machine, and your data are such and such collected during an in vitro observation. While you would naturally declare all this when you publish, there’s no guarantee anyone has an Ubuntu laptop with a working RStudio setup around, so even if you provide all the code, it might be for nothing.

If, however, you put it on Code Ocean, like this, it makes all the relevant code available, and capable of being inspected and run unmodified with a click, or being fiddled with if a colleague is wondering about a certain piece. It works through a single link and web app, cross platform, and can even be embedded on a webpage like a document or video. (I’m going to try to do that below, but our backend is a little finicky. The capsule itself is here.)

More than that, though, the Compute Capsule can be repurposed by others with new data and modifications. Maybe the technique you put online is a general purpose RNA sequence analysis tool that works as long as you feed it properly formatted data, and that’s something others would have had to code from scratch in order to take advantage of some platforms.

Well, they can just clone your capsule, run it with their own data and get their own results in addition to verifying your own. This can be done via the Code Ocean website or just by downloading a zip file of the whole thing and getting it running on their own computer, if they happen to have a compatible setup. A few more example capsules can be found here.

Screenshot of the Code Ocean workbench environment.
Image Credits: Code Ocean

This sort of cross-pollination of research techniques is as old as science, but modern data-heavy experimentation often ends up siloed because it can’t easily be shared and verified even though the code is technically available. That means other researchers move on, build their own thing and further reinforce the silo system.

Right now there are about 2,000 public compute capsules on Code Ocean, most of which are associated with a published paper. Most have also been used by others, either to replicate or try something new, and some, like ultra-specific open source code libraries, have been used by thousands.

Naturally there are security concerns when working with proprietary or medically sensitive data, and the enterprise product allows the whole system to run on a private cloud platform. That way it would be more of an internal tool, and at major research institutions that in itself could be quite useful.

Data is the world’s most valuable (and vulnerable) resource

Code Ocean hopes that by being as inclusive as possible in terms of codebases, platforms, compute services and so on will make for a more collaborative environment at the cutting edge.

Clearly that ambition is shared by others, as the the company has raised $21 million so far, $6 million of which was in previously undisclosed investments and $15 million in an A round announced today. The A round was led by Battery Ventures, with Digitalis Ventures, EBSCO and Vaal Partners participating as well as numerous others.

The money will allow the company to further develop, scale and promote its platform. With luck they’ll soon find themselves among the rarefied air often breathed by this sort of savvy SaaS — necessary, deeply integrated and profitable.

 

More TechCrunch

The problem is not the media, but the message.

Apple’s ‘Crush’ ad is disgusting

Ever wonder why conversational AI like ChatGPT says “Sorry, I can’t do that” or some other polite refusal? OpenAI is offering a limited look at the reasoning behind its own…

OpenAI offers a peek behind the curtain of its AI’s secret instructions

The federal government agency responsible for granting patents and trademarks is alerting thousands of filers whose private addresses were exposed following a second data spill in as many years. The…

US Patent and Trademark Office confirms another leak of filers’ address data

As part of an investigation into people involved in the pro-independence movement in Catalonia, the Spanish police obtained information from the encrypted services Wire and Proton, which helped the authorities…

Encrypted services Apple, Proton and Wire helped Spanish police identify activist

Match Group, the company that owns several dating apps, including Tinder and Hinge, released its first-quarter earnings report on Tuesday, which shows that Tinder’s paying user base has decreased for…

Match looks to Hinge as Tinder fails

Private social networking is making a comeback. Gratitude Plus, a startup that aims to shift social media in a more positive direction, is expanding its wellness-focused, personal reflections journal to…

Gratitude Plus makes social networking positive, private and personal

With venture totals slipping year-over-year in key markets like the United States, and concern that venture firms themselves are struggling to raise more capital, founders might be worried. After all,…

Can AI help founders fundraise more quickly and easily?

Google has found a way to bring a variation of its clever “Circle to Search” gesture to iPhone users. The new interaction, launched in January, allows Android users to search…

Google brings a variation on ‘Circle to Search’ to iPhone users

A new sculpture going live on Wednesday in the Flatiron South Public Plaza in New York is not your typical artwork. It combines technology, sociology, anthropology and art to let…

Always-on video portal lets people in NYC and Dublin interact in real time

Apple’s iPad event had a lot to like. New iPads with new chips and new sizes, a new Apple Pencil, and even some software updates. If you are a big…

TechCrunch Minute: When did iPads get as expensive as MacBooks?

Autonomous, AI-based players are coming to a gaming experience near you, and a new startup, Altera, is joining the fray to build this new guard of AI agents. The company announced…

Bye-bye bots: Altera’s game-playing AI agents get backing from Eric Schmidt

Google DeepMind has taken the wraps off a new version of AlphaFold, their transformative machine learning model that predicts the shape and behavior of proteins. AlphaFold 3 is not only…

Google DeepMind debuts huge AlphaFold update and free proteomics-as-a-service web app

Uber plans to deliver more perks to Uber One members, like member-exclusive events, in a bid to gain more revenue through subscriptions.  “You will see more member-exclusives coming up where…

Uber promises member exclusives as Uber One passes $1B run-rate

We’ve all seen them. The inspector with a clipboard, walking around a building, ticking off the last time the fire extinguishers were checked, or if all the lights are working.…

Checkfirst raises $1.5M pre-seed to apply AI to remote inspections and audits

Close to a decade ago, brothers Aviv and Matteo Shapira co-founded a company, Replay, that created a video format for 360-degree replays — the sorts of replays that have become…

Controversial drone company Xtend leans into defense with new $40 million round

Usually, when something starts to rot, it gets pitched in the trash. But Joanne Rodriguez wants to turn the concept of rot on its head by growing fungus on trash…

Mycocycle uses mushrooms to upcycle old tires and construction waste

Monzo has raised another £150 million ($190 million), as the challenger bank looks to expand its presence internationally — particularly in the U.S. The new round comes just two months…

UK challenger bank Monzo nabs another $190M as US expansion beckons

iRobot has announced the successor to longtime CEO, Colin Angle. Gary Cohen, who previous held chief executive role at Timex and Qualitor Automotive, will be heading up the company, marking a major…

iRobot names former Timex head Gary Cohen as CEO

Reddit — now a publicly-traded company with more scrutiny on revenue growth — is putting a big focus on boosting its international audience, starting with francophones. In their first-ever earnings…

Reddit tests automatic, whole-site translation into French using LLM-based AI

Mushrooms continue to be a big area for alternative proteins. Canada-based Maia Farms recently raised $1.7 million to develop a blend of mushroom and plant-based protein using biomass fermentation. There’s…

Meati Foods bites into another $100M amid growth to 7,000 retail locations

Cleaning the outside of buildings is a dirty job, and it’s also dangerous. Lucid Bots came on the scene in 2018 with its Sherpa line of drones to clean windows…

Lucid Bots secures $9M for drones to clean more than your windows

High interest rates and financial pressures make it more important than ever for finance teams to have a better handle on their cash flow, and several startups are hoping to…

Israeli startup Panax raises a $10M Series A for its AI-driven cash flow management platform

The European Union has deepened the investigation of Elon Musk-owned social network, X, that it opened back in December under the bloc’s online governance and content moderation rulebook, the Digital Services Act…

EU grills Elon Musk’s X about content moderation and deepfake risks

For the founders of Atlan, a data governance startup, data has always been at the heart of what they do, even before they launched the company. In fact, co-founders Prukalpa…

Atlan scores $105M for its data control plane, as LLMs boost importance of data

It is estimated that about 2 billion people, especially those in lower- and middle-income countries, lack access to quality and affordable essential medicines. The situation is exacerbated by low-quality or even killer…

Axmed raises $2M from Founderful to streamline drug supply chains in underserved markets

For decades, the Global Positioning System (GPS) has maintained a de facto monopoly on positioning, navigation and timing, because it’s cheap and already integrated into billions of devices around the…

Xona Space Systems closes $19M Series A to build out ultra-accurate GPS alternative

Bankruptcy lawyers representing customers impacted by the dramatic crash of cryptocurrency exchange FTX 17 months ago say that the vast majority of victims will receive their money back — plus interest. The…

FTX crypto fraud victims to get their money back — plus interest

On Wednesday, Google launched its digital wallet in India with local integrations, nearly two years after the app was relaunched as a digital wallet platform in the U.S. As TechCrunch exclusively reported last month,…

Google Wallet is now available in India

Bluesky has launched a new product roadmap for the coming months. The decentralized social network said on Tuesday that it is planning to introduce direct messages, support for videos, improved…

Bluesky to add DMs, video support and in-app custom feed curation

Samsung Medison, a medical device unit of Samsung Electronics that specializes in developing diagnostic imaging devices, said on Wednesday it plans to acquire Sonio, a Paris-based startup that makes AI-powered software…

Samsung Medison to acquire French AI ultrasound startup Sonio for $92.7M