Startups

TechCrunch+ roundup: New VC rules, AI biotech investor survey, Instagram ad case study

Comment

Houses in the Sea Cliff neighborhood of San Francisco, California, US, on Thursday, Dec. 15, 2022. California home sales plunged this year as soaring interest rates held back buyers in the costly state. Photographer: David Paul Morris/Bloomberg via Getty Images
Image Credits: Bloomberg (opens in a new window) / Getty Images

When a cat is scared, it may hide under the couch; a startled fish will swim into a dark hole. And when humans feel uneasy, we tell ourselves stories.

An example: “growth at all costs” is a fairy tale made possible by cheap money that helped venture capitalists set expectations for founders — and each other — for years.

Similarly, “everyone needs 18-24 months of runway” is a nice motto, but when it takes three times longer to raise a round than it used to, it may no longer be useful advice.

“These ‘VCisms’ borne out of an era of plenty have permeated boardrooms and investor meetings everywhere,” notes Neotribes Ventures partner Rebecca Mitchem in a TechCrunch+ post this morning.


Full TechCrunch+ articles are only available to members.
Use discount code TCPLUSROUNDUP to save 20% off a one- or two-year subscription.


It’s time to ask ourselves if these VCisms are still relevant or if it’s time to change.

In a data-driven piece that looks at post-money valuations, deal sizes and dilution rates going back to 2012, Mitchem says we’re now heading into a new era where the tech industry will embrace “growth at reasonable costs.”

Founders can continue to water down their ownership by pursuing fat rounds, or they can decide to grow more slowly, which will leave everyone involved with a larger stake over time.

“While it may feel counterintuitive, given the recent market environment, the value of the equity for all parties — investors, founders and employees — is higher in the more conservative growth scenario,” says Mitchem.

Thanks very much for reading TC+ this week,

Walter Thompson
Editorial Manager, TechCrunch+
@yourprotagonist

The rules of VC are changing: Here’s what founders should be considering in the new era

6 investors discuss why AI is more than just a buzzword in biotech

Digital image of artificial intelligence human brain on black background.
Image Credits: Andriy Onufriyenko (opens in a new window) / Getty Images

Biotech firms widely use AI and machine learning to reduce R&D spending and bring products to market faster, but “the bigger question for investors is getting a better understanding of what exactly AI is attempting to model and predict,” says Shaq Vayda, principal at Lux Capital.

In her latest investor survey, Anna Heim spoke to six biotech investors about where AI creates value, short-term market shifts, and how they’d like to be approached by founders:

  • Robert Mittendorff, M.D, general partner and head of healthcare, B Capital
  • James Coates, health and human performance principal, Decisive Point
  • Shaq Vayda, principal, Lux Capital
  • Franck Lescure, partner, Elaia Partners
  • Francisco Dopazo, general partner, Humboldt Fund
  • Sarah Guo, founder, Conviction

6 investors discuss why AI is more than just a buzzword in biotech

Which Instagram ad placement is more cost-effective: Reels, Feed Posts or Stories?

Row of ice creams with different amounts of scoops
Image Credits: Jonathan Knowles (opens in a new window) / Getty Images

Consumer-facing startups are spending more on platforms like TikTok and Instagram to reach customers, but which ad products offer the best return?

In a case study based on Instagram campaigns for a site that facilitates bookings for freelance beauty professionals, digital marketer Angelina Liparteliani looked at Instagram Reels, Feed Posts and Stories.

Her highly detailed breakdown includes examples of the ads used in various campaigns, the process she used for optimizing creative materials and a cost-per-click analysis that shows how she reduced CPC from $1.51 to 17 cents.

“Definitely don’t chase trends,” advises Liparteliani. “Diversify your ad strategy, test different ideas and don’t give up if your ad doesn’t show results right away.”

Which Instagram ad placement is more cost-effective: Reels, Feed Posts or Stories?

Pitch Deck Teardown: MedCrypt’s $25M Series B deck

Image Credits: Medcrypt (opens in a new window)

Many medical devices are just as vulnerable to cybersecurity threats as other IoT products, which is why Y Combinator graduate MedCrypt creates software to protect patients.

The company predicts that manufacturers will need to secure $1 trillion of “new and legacy” devices over the next three years, a truly tantalizing TAM.

After redacting some customer adoption details, MedCrypt’s founders shared with TC+ the 12-slide deck that helped it raise a $25 million Series B:

  • Cover slide
  • Problem slide
  • Target audience/market size slide
  • Opportunity slide
  • Mission slide
  • Product slide: Vulnerability tracking
  • Product slide: Behavior monitoring
  • Product slide: Cryptography
  • Product slide: MedISAO
  • Team slide
  • Summary/traction slide

Pitch Deck Teardown: MedCrypt’s $25M Series B deck

Dear Sophie: When can I register my employee for the H-1B lottery?

lone figure at entrance to maze hedge that has an American flag at the center
Image Credits: Bryce Durbin/TechCrunch

Dear Sophie,

We’re a pre-seed startup thinking about sponsoring an early employee’s H-1B visa to stay in the U.S. and work for us.

How does the process work?

— Seeking in San Mateo

Dear Sophie: When can I register my employee for the H-1B lottery?

A guide to navigating your first 90 days as a new CISO

Red Colored Navigational Compass on Red Background Directly Above View.
Image Credits: MirageC (opens in a new window) / Getty Images

I’m used to working under pressure, but taking a job as a chief information security officer sounds extraordinarily stressful: People are far more likely to learn about your failures than your successes.

Managing the cybersecurity needs of an entire organization is “a big job that touches just about every part of the organization,” says Heather Gantt-Evans, CISO at SailPoint.

She’s written a guide for incoming CISOs that contains a framework for setting goals, creating action plans and, most importantly, documenting risk.

“The first 90 days of a new CISO’s term are critical,” writes Gantt-Evans. “They’re the best chance you’ll ever have to research, gather documentation and assess where things stand and how they can be improved.”

A guide to navigating your first 90 days as a new CISO

In a turbulent market, it’s time to get methodical about sales

Teacher preparing pencils for school day; aligning product team with product vision
Image Credits: Peter Dazeley (opens in a new window) / Getty Images

Many SaaS sales teams haven’t worked in an environment where so many customers are cutting back on spending, and it shows: When everyone’s in the mood to buy, it’s less important to develop a critical understanding of your customer’s needs.

“Sellers shouldn’t hop right into pushing features,” advises Steve Goldberg, chief revenue officer at Salesloft. “They should illustrate the unsustainable nature of a customer’s current behaviors and processes.”

In this post, Goldberg looks at MEDDPICC and design thinking, two sales methodologies that are “particularly effective when times get tough.”

In a turbulent market, it’s time to get methodical about sales

More TechCrunch

Try to imagine the number of parts that go into making a rocket engine. Now imagine requesting and comparing quotes for each of those parts, getting approvals to purchase the…

Engineer brothers found Forge to modernize hardware procurement

The Raspberry Pi 5, the small-but-mighty computer that has become quite popular with tech hobbyists and industrial companies, is now also an AI computer. The company just released the AI…

Raspberry Pi partners with Hailo for its AI extension kit

When Stacklet’s founders, Travis Stanfield and Kapil Thangavelu, came out of Capital One in 2020 to launch their startup, most companies weren’t all that concerned with constraining cloud costs. But…

Stacklet sees demand grow as companies take cloud cost control more seriously

Fivetran’s Managed Data Lake Service aims to remove the repetitive work of managing data lakes.

Fivetran launches a managed data lake service

Lance Riedel and Nigel Daley both spent decades in search discovery, but it was while working at Pinterest that they began trying to understand how to use search engines to…

How a couple of former Pinterest search experts caught Biz Stone’s attention

GetWhy helps businesses carry out market studies and extract insights from video-based interviews using AI.

GetWhy, a market research AI platform that extracts insights from video interviews, raises $34.5M

AI-powered virtual physical therapy platform Sword Health has seen its valuation soar 50% to $3 billion.

Sword Health raises $130 million and its valuation soars to $3 billion

Jeffrey Katzenberg and Sujay Jaswa, along with three general partners, manage $1.5 billion in assets today through their Build, Venture and Seed strategies.

WndrCo officially gets into venture capital with fresh $460M across two funds

The startup targets the middle ground between platforms that offer rigid templates, and those that facilitate a full-control approach.

Storyblok raises $80M to add more AI to its ‘headless’ CMS aimed at non-technical people

The startup has been pursuing a ground-up redesign of a well-understood technology.

‘Star Wars’ lasers and waterfalls of molten salt: How Xcimer plans to make fusion power happen

Sékr, a startup that offers a mobile app for outdoor enthusiasts and campers, is launching a new AI tool for planning road trips. The new tool, called Copilot, is available…

Travel app Sékr can plan your next road trip with its new AI tool

OpenAI’s chatbot ChatGPT has been down for several users across the globe for the last few hours.

OpenAI fixes the issue that caused ChatGPT outage for several hours

Microsoft’s education-focused flavor of its cloud productivity suite, Microsoft 365 Education, is facing investigation in the European Union. Privacy rights non-profit noyb has just lodged two complaints with Austria’s data…

Microsoft hit with EU privacy complaints over schools’ use of 365 Education suite

Since the shock of Russia’s 2022 invasion of Ukraine, solar energy has been having a moment in Europe. Electricity prices have been going up while the investment required to get…

Samara is accelerating the energy transition in Spain one solar panel at a time

Featured Article

DEI backlash: Stay up-to-date on the latest legal and corporate challenges

It’s clear that this year will be a turning point for DEI.

16 hours ago
DEI backlash: Stay up-to-date on the latest legal and corporate challenges

The keynote will be focused on Apple’s software offerings and the developers that power them, including the latest versions of iOS, iPadOS, macOS, tvOS, visionOS and watchOS.

Watch Apple kick off WWDC 2024 right here

Hello and welcome back to TechCrunch Space. Unfortunately, Boeing’s Starliner launch was delayed yet again, this time due to issues with one of the three redundant computers used by United…

TechCrunch Space: China’s victory

The court ruling said that Fearless Fund’s Strivers Grant likely violates the Civil Rights Act of 1866, which bans the use of race in contracts.

An appeals court rules that VC Fearless Fund cannot issue grants to Black women, but the fight continues

Instagram Threads is rolling out the ability for users to signal which sort of posts they wanted to see more or less of by swiping.

You can now customize your For You feed on Threads using swipes

The Japanese billionaire who commissioned SpaceX for a private mission around the moon on a Starship rocket has abruptly canceled the project, citing ongoing uncertainties around when the launch vehicle…

Japanese billionaire pulls plug on private ‘dearMoon’ lunar Starship mission

Malicious actors are abusing generative AI music tools to create homophobic, racist, and propagandic songs — and publishing guides instructing others how to do so. According to ActiveFence, a service…

People are using AI music generators to create hateful songs

As WWDC 2024 nears, all sorts of rumors and leaks have emerged about what iOS 18 and its AI-powered apps and features have in store.

What to expect from Apple’s AI-powered iOS 18 at WWDC

Dallas is the second city that Cruise is easing its way back into after pulling its entire U.S. fleet late last year.

GM’s Cruise is testing robotaxis in Dallas again

Featured Article

After raising $100M, AI fintech LoanSnap is being sued, fined, evicted

The company has been sued by at least seven creditors, including Wells Fargo.

20 hours ago
After raising $100M, AI fintech LoanSnap is being sued, fined, evicted

Featured Article

Sonos Ace review: A high-priced contender

The Ace are a contender in a crowded market, but they’re still in search of that magic bullet to truly let them stand out from the pack.

20 hours ago
Sonos Ace review: A high-priced contender

The change would see Instagram becoming more like the free version of YouTube, which requires users to view ads before and in the middle of watching videos.

Instagram confirms test of ‘unskippable’ ads

Commerce platform Shopify has acquired Checkout Blocks, allowing Shopify Plus merchants to make no-code customizations in their checkout to enhance customer experience and potentially boost sales.  Checkout Blocks, which debuted…

Shopify acquires Checkout Blocks, a checkout customization app

After the Digital Markets Act (DMA) forced Apple to allow third-party app stores for iOS in Europe, several developers have launched alternative stores, like the AltStore and MacPaw’s Setapp (currently…

Aptoide launches its alternative iOS game store in the EU

Time is relentless and, right now, it’s no friend to procrastination-prone early-stage startup founders. The application window for Startup Battlefield 200 (SB 200) at TechCrunch Disrupt 2024 slams shut in…

One week left: Apply to TC Disrupt Startup Battlefield 200

Cloudera, the once high-flying Hadoop startup, raised $1 billion and went public in 2018 before being acquired by private equity for $5.3 billion in 2021. Today, the company announced that…

Cloudera acquires Verta to bring some AI chops to its data platform