Startups

TechCrunch+ roundup: New VC rules, AI biotech investor survey, Instagram ad case study

Comment

Houses in the Sea Cliff neighborhood of San Francisco, California, US, on Thursday, Dec. 15, 2022. California home sales plunged this year as soaring interest rates held back buyers in the costly state. Photographer: David Paul Morris/Bloomberg via Getty Images
Image Credits: Bloomberg (opens in a new window) / Getty Images

When a cat is scared, it may hide under the couch; a startled fish will swim into a dark hole. And when humans feel uneasy, we tell ourselves stories.

An example: “growth at all costs” is a fairy tale made possible by cheap money that helped venture capitalists set expectations for founders — and each other — for years.

Similarly, “everyone needs 18-24 months of runway” is a nice motto, but when it takes three times longer to raise a round than it used to, it may no longer be useful advice.

“These ‘VCisms’ borne out of an era of plenty have permeated boardrooms and investor meetings everywhere,” notes Neotribes Ventures partner Rebecca Mitchem in a TechCrunch+ post this morning.


Full TechCrunch+ articles are only available to members.
Use discount code TCPLUSROUNDUP to save 20% off a one- or two-year subscription.


It’s time to ask ourselves if these VCisms are still relevant or if it’s time to change.

In a data-driven piece that looks at post-money valuations, deal sizes and dilution rates going back to 2012, Mitchem says we’re now heading into a new era where the tech industry will embrace “growth at reasonable costs.”

Founders can continue to water down their ownership by pursuing fat rounds, or they can decide to grow more slowly, which will leave everyone involved with a larger stake over time.

“While it may feel counterintuitive, given the recent market environment, the value of the equity for all parties — investors, founders and employees — is higher in the more conservative growth scenario,” says Mitchem.

Thanks very much for reading TC+ this week,

Walter Thompson
Editorial Manager, TechCrunch+
@yourprotagonist

The rules of VC are changing: Here’s what founders should be considering in the new era

6 investors discuss why AI is more than just a buzzword in biotech

Digital image of artificial intelligence human brain on black background.
Image Credits: Andriy Onufriyenko (opens in a new window) / Getty Images

Biotech firms widely use AI and machine learning to reduce R&D spending and bring products to market faster, but “the bigger question for investors is getting a better understanding of what exactly AI is attempting to model and predict,” says Shaq Vayda, principal at Lux Capital.

In her latest investor survey, Anna Heim spoke to six biotech investors about where AI creates value, short-term market shifts, and how they’d like to be approached by founders:

  • Robert Mittendorff, M.D, general partner and head of healthcare, B Capital
  • James Coates, health and human performance principal, Decisive Point
  • Shaq Vayda, principal, Lux Capital
  • Franck Lescure, partner, Elaia Partners
  • Francisco Dopazo, general partner, Humboldt Fund
  • Sarah Guo, founder, Conviction

6 investors discuss why AI is more than just a buzzword in biotech

Which Instagram ad placement is more cost-effective: Reels, Feed Posts or Stories?

Row of ice creams with different amounts of scoops
Image Credits: Jonathan Knowles (opens in a new window) / Getty Images

Consumer-facing startups are spending more on platforms like TikTok and Instagram to reach customers, but which ad products offer the best return?

In a case study based on Instagram campaigns for a site that facilitates bookings for freelance beauty professionals, digital marketer Angelina Liparteliani looked at Instagram Reels, Feed Posts and Stories.

Her highly detailed breakdown includes examples of the ads used in various campaigns, the process she used for optimizing creative materials and a cost-per-click analysis that shows how she reduced CPC from $1.51 to 17 cents.

“Definitely don’t chase trends,” advises Liparteliani. “Diversify your ad strategy, test different ideas and don’t give up if your ad doesn’t show results right away.”

Which Instagram ad placement is more cost-effective: Reels, Feed Posts or Stories?

Pitch Deck Teardown: MedCrypt’s $25M Series B deck

Image Credits: Medcrypt (opens in a new window)

Many medical devices are just as vulnerable to cybersecurity threats as other IoT products, which is why Y Combinator graduate MedCrypt creates software to protect patients.

The company predicts that manufacturers will need to secure $1 trillion of “new and legacy” devices over the next three years, a truly tantalizing TAM.

After redacting some customer adoption details, MedCrypt’s founders shared with TC+ the 12-slide deck that helped it raise a $25 million Series B:

  • Cover slide
  • Problem slide
  • Target audience/market size slide
  • Opportunity slide
  • Mission slide
  • Product slide: Vulnerability tracking
  • Product slide: Behavior monitoring
  • Product slide: Cryptography
  • Product slide: MedISAO
  • Team slide
  • Summary/traction slide

Pitch Deck Teardown: MedCrypt’s $25M Series B deck

Dear Sophie: When can I register my employee for the H-1B lottery?

lone figure at entrance to maze hedge that has an American flag at the center
Image Credits: Bryce Durbin/TechCrunch

Dear Sophie,

We’re a pre-seed startup thinking about sponsoring an early employee’s H-1B visa to stay in the U.S. and work for us.

How does the process work?

— Seeking in San Mateo

Dear Sophie: When can I register my employee for the H-1B lottery?

A guide to navigating your first 90 days as a new CISO

Red Colored Navigational Compass on Red Background Directly Above View.
Image Credits: MirageC (opens in a new window) / Getty Images

I’m used to working under pressure, but taking a job as a chief information security officer sounds extraordinarily stressful: People are far more likely to learn about your failures than your successes.

Managing the cybersecurity needs of an entire organization is “a big job that touches just about every part of the organization,” says Heather Gantt-Evans, CISO at SailPoint.

She’s written a guide for incoming CISOs that contains a framework for setting goals, creating action plans and, most importantly, documenting risk.

“The first 90 days of a new CISO’s term are critical,” writes Gantt-Evans. “They’re the best chance you’ll ever have to research, gather documentation and assess where things stand and how they can be improved.”

A guide to navigating your first 90 days as a new CISO

In a turbulent market, it’s time to get methodical about sales

Teacher preparing pencils for school day; aligning product team with product vision
Image Credits: Peter Dazeley (opens in a new window) / Getty Images

Many SaaS sales teams haven’t worked in an environment where so many customers are cutting back on spending, and it shows: When everyone’s in the mood to buy, it’s less important to develop a critical understanding of your customer’s needs.

“Sellers shouldn’t hop right into pushing features,” advises Steve Goldberg, chief revenue officer at Salesloft. “They should illustrate the unsustainable nature of a customer’s current behaviors and processes.”

In this post, Goldberg looks at MEDDPICC and design thinking, two sales methodologies that are “particularly effective when times get tough.”

In a turbulent market, it’s time to get methodical about sales

More TechCrunch

After two years of preparation and four delays over the past several months due to technical glitches, Indian space startup Agnikul has successfully launched its first sub-orbital test vehicle, powered…

India’s Agnikul launches 3D-printed rocket in sub-orbital test after initial delays

Struggling EV startup Fisker has laid off hundreds of employees in a bid to stay alive, as it continues to search for funding, a buyout or prepare for bankruptcy. Workers…

Fisker cuts hundreds of workers in bid to keep EV startup alive

Chinese EV manufacturers face a new challenge in their pursuit of U.S. customers: a new House bill that would limit or ban the introduction of their connected vehicles. The bill,…

Chinese EV makers, and their connected vehicles, targeted by new House bill

With the release of iOS 18 later this year, Apple may again borrow ideas third-party apps. This time it’s Arc that could be among those affected.

Is Apple planning to ‘sherlock’ Arc?

TechCrunch Disrupt 2024 will be in San Francisco on October 28–30, and we’re already excited! This is the startup world’s main event, and it’s where you’ll find the knowledge, tools…

Meet Visa, Mercury, Artisan, Golub Capital and more at TC Disrupt 2024

Featured Article

The women in AI making a difference

As a part of a multi-part series, TechCrunch is highlighting women innovators — from academics to policymakers —in the field of AI.

10 hours ago
The women in AI making a difference

Cadillac may seem a bit too traditional to hang its driving cap on EVs. And yet, that hasn’t stopped the GM brand from rolling out — or at least showing…

The Cadillac Optiq EV starts at $54,000 and is designed to hook young hipsters

Ifeel is being offered as part of an employer’s or insurance provider’s healthcare coverage.

Mental health insurance platform ifeel raises a $20 million Series B

Instead of opening the user’s actual browser or a WebView, Custom Tabs let users remain in their app while browsing.

Google Chrome becomes a ‘picture-in-picture’ app

Sanil Chawla remembers the meetings he had with countless artists in college. Those creatives were looking for one thing: sustainable economic infrastructure that could help them scale rather than drown…

Slingshot raises $2.2 million to provide financial services to artists

A startup called Firefly that’s tackling the thorny and growing issue of cloud asset management with an “infrastructure as code” solution has raised $23 million in funding. That comes on…

Firefly forges on after co-founder murdered by Hamas

Mistral, the French AI startup backed by Microsoft and valued at $6 billion, has released its first generative AI model for coding, dubbed Codestral. Like other code-generating models, Codestral is…

Mistral releases Codestral, its first generative AI model for code

Pinterest announced today that it is evolving its Creator Inclusion Fund to now be called the Pinterest Inclusion Fund. Pinterest teamed up with Shopify’s Build Black and Build Native programs…

Pinterest expands its Creator Fund to allow founders

Alex Taub, a longtime founder with multiple exits under his belt, believes it’s time to disrupt the meme industry. “I have this big thesis that meme tech is going to…

This founder says meme tech is the next big thing

Lux, the startup behind popular pro photography app Halide and others, is venturing into video with its latest app launch. On Wednesday, the company announced Kino, a new video capture app…

Kino is a new iPhone app for videographers from the makers of Halide

DevOps startup Harness has shown itself to be an ambitious company, building a broad platform of services while also dabbling in M&A when it made sense to fill in functionality.…

Harness snags Split.io as it goes all in on feature flags and experiments

Microsoft’s Copilot, a generative AI-powered tool that can generate text as well as answer specific questions, is now available as an in-app chatbot on Telegram, the instant messaging app.  Currently…

Microsoft’s Copilot is now on Telegram

HBO’s new documentary, “MoviePass, MovieCrash,” tells a story that many of us know about: how MoviePass, the subscription-based movie ticketing startup, was a catastrophic failure. After a series of mishaps…

MoviePass co-founders speak their truth in HBO’s new documentary 

The watch features a variety of different 3D games, unlocking more play time the more kids move.

Fitbit’s new kid smartwatch is a little Wiimote, a little Tamagotchi

In the video, a crowd is roaring at a packed summer music festival. As a beat starts playing over the speakers, the performer finally walks onstage: It’s the Joker. Clad…

Discord has become an unlikely center for the generative AI boom

After the Wirecard scandal, Germany’s financial regulator BaFin started to look more closely at young fintech startups that wanted to grow at a rapid pace — it’s better to be…

Germany’s financial regulator ends anti-money laundering cap on N26 signups after $10M fine

Among other things, this includes the ability to trace code from source to binary packages across both platforms, single sign-on support and unified project structures.

JFrog and GitHub team up to closely integrate their source code and binary platforms

The company’s public fund disbursement and e-commerce platform makes accepting school tuition and enabling educational enrichment more accessible. 

Tech startup Odyssey goes on journey to help states implement school choice programs

A new startup called Kinnect aims to help people privately save generational memories, traditions, recipes and more. The company’s app, launched this month, lets people create invite-only spaces where they…

Kinnect’s new app aims to help families record and store generational memories

Spotify has hiked its premium subscription in France by an eye-watering €0.13, in response to a new music-streaming tax.

Spotify hikes subscription price in France by 1.2% to match new music-streaming tax

The European Union has taken the wraps off the structure of the new AI Office, the ecosystem-building and oversight body that’s being established under the bloc’s AI Act. The risk-based…

With the EU AI Act incoming this summer, the bloc lays out its plan for AI governance

Solutions by Text, a company that gives people a way to pay their bills and apply for loans via text messaging, has secured $110 million in new growth funding. Edison…

Bootstrapped for over a decade, this Dallas company just secured $110M to help people pay bills by text

Owners of small- and medium-sized businesses check their bank balances daily to make financial decisions. But it’s entrepreneur Yoseph West’s assertion that there’s typically information and functions missing from bank…

Relay raises $32.2 million to help smaller businesses manage their cash flow

When other firms were investing and raising eye-popping sums, Clean Energy Ventures took a different approach. It appears to be paying off.

How Clean Energy Ventures avoided the pandemic bubble and raised a $305M fund

PwC, the management consulting giant, will become OpenAI’s biggest customer to date, covering 100,000 users.

OpenAI signs 100K PwC workers to ChatGPT’s enterprise tier as PwC becomes its first resale partner