Biotech & Health

TechCrunch+ roundup: 7 VCs who are taking pitches, AI best practices, zero-based budgeting

Comment

Directly Above San Francisco Bay Bridge
Image Credits: JasonDoiy (opens in a new window) / Getty Images

It’s too early to determine whether SVB’s downfall heralds a new era for venture capital, but based on anecdotal evidence, off-the-record discussions and chats with co-workers, it seems like we’re back to business as usual as far as pre-revenue startup fundraising is concerned.

Not a scientific sampling, but I noticed that several investors signaled this week on Twitter that they remain interested in talking to founders who are still at the idea stage.

I shy away from sharing hot takes, but here’s one: With contagion contained, the VC community feels good about writing smallish checks for pre-revenue startups, but Series A and up? Más o menos.


Full TechCrunch+ articles are only available to members.
Use discount code TCPLUSROUNDUP to save 20% off a one- or two-year subscription.


Before Silicon Valley Bank crashed, I asked seven VCs about the startups they’re interested in backing right now, how they prefer to be approached and whether they could share any tips for first-time founders.

As long as this downturn persists, this investor Q&A will be a monthly TC+ column. If you’re a recently laid-off worker considering striking out on your own, an H-1B employee who’s had it up to here or just looking for tips and advice that can help you connect with early-stage investors, please read and share.

If you’re an investor who wants to be included in future columns, email guestcolumns@techcrunch.com with “How to pitch me” in the subject line.

Thanks very much to everyone who took the time to respond to these questions in such detail. There’s plenty of tactical advice here, and much more to come.

Here’s who participated:

Have a great weekend,

Walter Thompson
Editorial Manager, TechCrunch+
@yourprotagonist

How to pitch me: 7 investors discuss what they’re looking for in March 2023

Best practices for changing times: How founders should leverage AI and ML in 2023

As startups navigate a disruptive season, they need to innovate to remain competitive. Artificial intelligence and machine learning may finally be capable of making that a reality.
Image Credits: Getty Images

We don’t run many articles promoting basic best practices. Suggestions like “listen to your customers” and “make data-driven decisions” are so general, they’re hard to implement.

But now that AI-driven solutions are offering search results, producing poems and generating illustrations on demand, startups need a plan for creating customized user experiences, according to Ab Gaur, founder and CEO of Verticurl.

“While excessive or unhelpful customer data can clog content pipelines, the right information can power hyper-personalization at scale,” he writes.

Best practices for leveraging artificial intelligence and machine learning in 2023

Zero-based budgeting: A proven framework for extending runway

Zero-based budgeting (ZBB) is one of the most aggressive budgeting methods to cut burn to the bare minimum.
Image Credits: Getty Images

It’s critical to make every dollar count in this environment, but pulling back too much in the wrong places can reduce momentum across your entire organization.

Instead of simply trimming a little off the top, more startups are turning to zero-based budgeting, an aggressive tactic in which founders return to square one for every budget period “to verify all of the line items are relevant and cost-effective,” writes FP&A analyst Healy Jones.

“The best founders look for a framework to strategically cut burn while keeping their startup’s value drivers functioning.”

Zero-based budgeting: A proven framework for extending runway

5 strategies for biotech startups to outlast a market downturn

To ensure survival, it’s essential to explore alternative funding methods rather than relying solely on classic fundraising.
Image Credits: Getty Images

Spinning up a biotech company is a massive undertaking. Compared to a SaaS startup, the investment required to build a team, acquire research funding and ensure regulatory compliance can be staggering.

Dr. James Coates, “a venture capitalist specializing in early-stage life science companies,” says biotech founders need to look beyond their investor networks to find additional money these days.

In his latest TC+ post, he shares five action items “that could help your biotech startup navigate a cooling fundraising environment.”

5 strategies for biotech startups to outlast a market downturn

Pitch Deck Teardown: StudentFinance’s $41M Series A deck

Image Credits: StudentFinance

Last month, we reported that European fintech startup StudentFinance landed a $41 million Series A to expand its service, which offers educational funding via income share agreements (ISAs).

This week, Haje Jan Kamps reviewed the company’s Series A deck, minus redactions for “sensitive revenue, cost and unit economics slides:”

  • Cover
  • Mission
  • Opportunity
  • Problem
  • Solution
  • Value proposition part 1
  • Value proposition part 2
  • Business model
  • Technology
  • Metrics
  • Road map (labeled “expansion”)
  • Geographic expansion (labeled “expansion”)
  • Growth history and trajectory (labeled “expansion”)
  • Team
  • Contact

Pitch Deck Teardown: StudentFinance’s $41M Series A deck

Dear Sophie: How can I return to the United States as a founder?

lone figure at entrance to maze hedge that has an American flag at the center
Image Credits: Bryce Durbin/TechCrunch

Dear Sophie,

I lived and worked in the United States on an L-1B for a year, and then changed to an H-1B for 2.5 years before I moved back to India (where I’m a citizen) and founded a startup.

Now I want to return to the U.S. to raise funds for my startup. What are my options for returning to the U.S. as a founder?

— Fast-Moving Founder

Dear Sophie: How can I return to the United States as a founder?

‘Trust is a hard thing to earn’: SVB’s closure could disproportionately affect Black founders

black-founder-svb
Image Credits: Bryce Durbin

Silicon Valley Bank’s federal takeover means former customers can access their funds, but some Black tech founders are concerned that its closure makes their uphill climb even steeper.

Because SVB’s startup-focused approach lowered barriers to banking services, it was a popular choice for many Black founders, reports Dominic-Madori Davis.

“Silicon Valley Bank was certainly willing to push the envelope and see what they could do, including investing in Black funds,” said Lightship Capital co-founder Brian Brackeen. “We don’t see that commitment from other banks.”

‘Trust is a hard thing to earn’: SVB’s closure could disproportionately affect Black founders

More TechCrunch

Paris-based Mistral AI, a startup working on open source Large Language Models — the building block for generative AI services — has been raising money at a $6 billion valuation,…

Sources: Mistral AI raising at a $6B valuation, SoftBank ‘not in’ but DST is

You can expect plenty of AI, but probably not a lot of hardware.

Google I/O 2024: What to expect

Dating apps and other social friend-finders are being put on notice: Dating app giant Bumble is looking to make more acquisitions.

Bumble says it’s looking to M&A to drive growth

When Class founder Michael Chasen was in college, he and a buddy came up with the idea for Blackboard, an online classroom organizational tool. His original company was acquired for…

Blackboard founder transforms Zoom add-on designed for teachers into business tool

Groww, an Indian investment app, has become one of the first startups from the country to shift its domicile back home.

Groww joins the first wave of Indian startups moving domiciles back home from US

Technology giant Dell notified customers on Thursday that it experienced a data breach involving customers’ names and physical addresses. In an email seen by TechCrunch and shared by several people…

Dell discloses data breach of customers’ physical addresses

Featured Article

Fairgen ‘boosts’ survey results using synthetic data and AI-generated responses

The Israeli startup has raised $5.5M for its platform that uses “statistical AI” to generate synthetic data that it says is as good as the real thing.

2 hours ago
Fairgen ‘boosts’ survey results using synthetic data and AI-generated responses

Hydrow, the at-home rowing machine maker, announced Thursday that it has acquired a majority stake in Speede Fitness, the company behind the AI-enabled strength training machine. The rowing startup also…

Rowing startup Hydrow acquires a majority stake in Speede Fitness as their CEO steps down

Call centers are embracing automation. There’s debate as to whether that’s a good thing, but it’s happening — and quite possibly accelerating. According to research firm TechSci Research, the global…

Retell AI lets companies build ‘voice agents’ to answer phone calls

TikTok is starting to automatically label AI-generated content that was made on other platforms, the company announced on Thursday. With this change, if a creator posts content on TikTok that…

TikTok will automatically label AI-generated content created on platforms like DALL·E 3

India’s mobile payments regulator is likely to extend the deadline for imposing market share caps on the popular UPI (unified payments interface) payments rail by one to two years, sources…

India likely to delay UPI market caps in win for PhonePe-Google Pay duopoly

Line Man Wongnai, an on-demand food delivery service in Thailand, is considering an initial public offering on a Thai exchange or the U.S. in 2025.

Thai food delivery app Line Man Wongnai weighs IPO in Thailand, US in 2025

The problem is not the media, but the message.

Apple’s ‘Crush’ ad is disgusting

Ever wonder why conversational AI like ChatGPT says “Sorry, I can’t do that” or some other polite refusal? OpenAI is offering a limited look at the reasoning behind its own…

OpenAI offers a peek behind the curtain of its AI’s secret instructions

The federal government agency responsible for granting patents and trademarks is alerting thousands of filers whose private addresses were exposed following a second data spill in as many years. The…

US Patent and Trademark Office confirms another leak of filers’ address data

As part of an investigation into people involved in the pro-independence movement in Catalonia, the Spanish police obtained information from the encrypted services Wire and Proton, which helped the authorities…

Encrypted services Apple, Proton and Wire helped Spanish police identify activist

Match Group, the company that owns several dating apps, including Tinder and Hinge, released its first-quarter earnings report on Tuesday, which shows that Tinder’s paying user base has decreased for…

Match looks to Hinge as Tinder fails

Private social networking is making a comeback. Gratitude Plus, a startup that aims to shift social media in a more positive direction, is expanding its wellness-focused, personal reflections journal to…

Gratitude Plus makes social networking positive, private and personal

With venture totals slipping year-over-year in key markets like the United States, and concern that venture firms themselves are struggling to raise more capital, founders might be worried. After all,…

Can AI help founders fundraise more quickly and easily?

Google has found a way to bring a variation of its clever “Circle to Search” gesture to iPhone users. The new interaction, launched in January, allows Android users to search…

Google brings a variation on ‘Circle to Search’ to iPhone users

A new sculpture going live on Wednesday in the Flatiron South Public Plaza in New York is not your typical artwork. It combines technology, sociology, anthropology and art to let…

Always-on video portal lets people in NYC and Dublin interact in real time

Apple’s iPad event had a lot to like. New iPads with new chips and new sizes, a new Apple Pencil, and even some software updates. If you are a big…

TechCrunch Minute: When did iPads get as expensive as MacBooks?

Autonomous, AI-based players are coming to a gaming experience near you, and a new startup, Altera, is joining the fray to build this new guard of AI agents. The company announced…

Bye-bye bots: Altera’s game-playing AI agents get backing from Eric Schmidt

Google DeepMind has taken the wraps off a new version of AlphaFold, their transformative machine learning model that predicts the shape and behavior of proteins. AlphaFold 3 is not only…

Google DeepMind debuts huge AlphaFold update and free proteomics-as-a-service web app

Uber plans to deliver more perks to Uber One members, like member-exclusive events, in a bid to gain more revenue through subscriptions.  “You will see more member-exclusives coming up where…

Uber promises member exclusives as Uber One passes $1B run-rate

We’ve all seen them. The inspector with a clipboard, walking around a building, ticking off the last time the fire extinguishers were checked, or if all the lights are working.…

Checkfirst raises $1.5M pre-seed to apply AI to remote inspections and audits

Close to a decade ago, brothers Aviv and Matteo Shapira co-founded a company, Replay, that created a video format for 360-degree replays — the sorts of replays that have become…

Controversial drone company Xtend leans into defense with new $40 million round

Usually, when something starts to rot, it gets pitched in the trash. But Joanne Rodriguez wants to turn the concept of rot on its head by growing fungus on trash…

Mycocycle uses mushrooms to upcycle old tires and construction waste

Monzo has raised another £150 million ($190 million), as the challenger bank looks to expand its presence internationally — particularly in the U.S. The new round comes just two months…

UK challenger bank Monzo nabs another $190M as US expansion beckons

iRobot has announced the successor to longtime CEO, Colin Angle. Gary Cohen, who previous held chief executive role at Timex and Qualitor Automotive, will be heading up the company, marking a major…

iRobot names former Timex head Gary Cohen as CEO